Doxycycline Capsules are used in the treatment of a variety of infections
caused by susceptible strains of Gram-positive and Gram-negative bacteria and
certain other micro-organisms.
• Respiratory tract infections: Pneumonia and other lower tract respiratory
tract infections due to susceptible strains of Streptococcus pneumoniae,
Haemophilia influenzae, Klebsiella pneumoniae and other organisms. Mycoplasma
pneumoniae pneumonia. Treatment of chronic bronchitis. Sinusitis.
• Urinary
tract infections: Infections caused by susceptible strains of Klebsiella
species, Enterobacter species. Escherichia coli, Streptococcus faecalis and
other organisms.
• Sexually transmitted diseases: Infections due to Chlamydia
trachomatis including uncomplicated urethral, endocervical or rectal infections.
Non-gonococcal, urethritis caused by Ureaplasma urealyticum. Chancroid
infections due to Calymmatobacterium granulomatis. Alternative drug in the
treatment of gonorrhoea and syphilis.
• Dermatological infections: Acne
vulgaris when antibiotic therapy is considered necessary.
Since doxycycline is a member of the tetracycline series of antibiotics, it
may be expected to be useful in the treatment of infections which respond to
other tetracyclines, such as:
• Ophthalmic infections: Due to susceptible strains of gonococci,
staphylococci and Haemophilus influenzae. Doxycycline Capsules are indicated in
the treatment of trachoma, although the infectious agent is not always
eliminated, as judged by immunofluorescence.
• Rickettsial infections: Rocky
Mountain spotted fever, typhus group, Q fever and Coxiella endocarditis and tick
fevers.
• Miscellaneous: Psittacosis, cholera, meliodosis, leptospirosis,
other infections due to susceptible strains of Yersinia species, Brucella
species (in combination with Streptomycin), Clostridium species, Francisella
tularensis and chloroquine-resistant falciparum malaria.
• Doxycycline
Capsules are indicated for prophylaxis in the following conditions: Scrub
typhus, travellers diarrhoea (enterotoxigenic Escherichia coli),
leptospirosis.