Mental Health in Focus: Rising Anxiety and Depression in Women with PCOS

Polycystic Ovary Syndrome (PCOS) is widely known for its physical symptoms—irregular periods, acne, weight gain, and infertility. But beneath the surface lies a growing mental health crisis. Recent studies have revealed that women with PCOS are significantly more likely to experience anxiety, depression, and elevated stress levels compared to those without the condition.

The Psychological Toll of PCOS

A 2025 study published in BMC Women’s Health found that nearly 29% of women with PCOS exhibited symptoms of adult separation anxiety, which strongly correlated with higher levels of depression, anxiety, and stress. These women also showed increased intolerance of uncertainty—a psychological trait linked to chronic worry and emotional dysregulation.

The authors concluded:

“Women with PCOS experience significantly higher levels of psychological symptoms including depression, anxiety, and elevated perceived stress, compared to women without PCOS. Moreover, our findings reveal that greater perceived stress and feelings of helplessness, along with lower self-efficacy, are strongly linked to increased psychological symptomatology.”

This underscores the urgent need for routine mental health screening and intervention programs focused on emotional regulation and stress management.

In Practice: Real-World Case Studies

Case Study 1: Sarah, 28 – “I thought I was just tired.”

Sarah, a marketing executive from Manchester, was diagnosed with PCOS at 24. Initially, she focused on managing her physical symptoms. But over time, she began experiencing persistent fatigue, low mood, and panic attacks.

“I thought I was just tired from work. But it got to the point where I couldn’t get out of bed. I didn’t realise how much PCOS was affecting my mental health.”

After being referred to a specialist, Sarah began cognitive behavioural therapy (CBT) alongside lifestyle changes. Within six months, her anxiety levels had significantly reduced

Case Study 2: Aisha, 35 – “I felt invisible.”

Aisha, a teacher from Birmingham, struggled with infertility and weight gain due to PCOS. The emotional toll led to social withdrawal and depressive episodes.

“I felt like no one understood. The physical symptoms were hard, but the emotional ones were worse. I felt invisible.”

With support from her GP and a local women’s health group, Aisha accessed counselling and joined a PCOS support network. She now advocates for mental health awareness in reproductive health.

What Can Employers and Healthcare Providers Do?

At Kays Medical, we believe in a holistic approach to workplace health. Here’s how employers and clinicians can support women with PCOS:

• Implement routine mental health screenings for women diagnosed with PCOS.
• Offer access to counselling services and Employee Assistance Programmes (EAPs).
• Educate line managers on the emotional impact of PCOS.
• Promote flexible working to accommodate medical appointments and mental health needs.

Conclusion

PCOS is more than a hormonal disorder – it’s a complex condition that deeply affects mental wellbeing. By recognising the psychological burden and integrating mental health support into care pathways, we can empower women to manage their condition more effectively and live fuller, healthier lives.